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Buy Zanaflex

Tizanidine is effective in both acute painful muscle spasm and spasticity of spinal and central genesis. Reduces spasticity and clonic cramps and spasms, as a result of which the resistance to passive movements decreases and the volume of active movements increases.

Central action muscle relaxant. Reduces the increased tone of skeletal muscles, relieves their spasm; reduces muscle resistance during passive movements, increases the strength of arbitrary contractions. The muscle-releasing effect of tizanidine is probably due to the inhibition of spinal polysynaptic reflexes, which is associated with a decrease in the release of excitatory amino acids from the presynaptic terminals of spinal interneurons, as well as stimulation of alpha2-adrenergic receptors. The transmission of arousal at neuromuscular synapses is not affected by tizanidine. See More →
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Learn more about Zanaflex (tizanidine)
The drug is used to reduce muscle stiffness and relieve muscle cramps (spasms) caused by certain diseases, such as multiple sclerosis and spinal cord damage. Reducing muscle spasms helps reduce pain and improve motor function. Tizanidine is a short-acting muscle relaxant acting by blocking certain nerve signals transmitted from the spinal cord to the brain (alpha-adrenergic agonist). See More →


Administration of the drug can lead to the formation of drug dependence, especially after administration for a long time or in high doses. In such cases, with a sharp cessation of intake, "withdrawal syndrome" is possible (anxiety, tremor, increased blood pressure, heart rate, increased muscle tension). If it is necessary to stop a regular long course of tizanidine, lower the dose gradually in accordance with the doctor's instructions - this will help avoid "withdrawal syndrome." For more information, contact your doctor or pharmacist

Muscle relaxants are a group of medicines widely used in modern neurology, traumatology, and even rheumatology. The mechanism of action of drugs is designed in such a way that these drugs reduce pathologically increased muscle tone, which often leads to soreness and spasticity. Muscle relaxants are drugs that are actively used in osteochondrosis, because over the course of this disease, aggravated pain is more often spastic. You should know which drugs are the most effective.

Muscle relaxants are not fully understood in terms of mechanism of action to date. The peculiarity of most muscle relaxers is that there is a blockade of relaxation of the skeletal muscle due to the blockade of H-cholinoreceptors in the synapses, which stops the supply of nerve impulse to the skeletal muscle. This is how the segmented muscle groups relax.

Spasticity is a condition associated with an involuntary increase in muscle tone that leads to resistance to normal body movements and can cause pain in some people.

The diagnosis of spasticity involves a thorough medical history and examination, with a particular focus on the potential causes of symptoms, in order to correctly diagnose and make treatment recommendations. Important factors to consider include any traumatic events that may have affected the CNS, changes in medications, harmful stimuli, and changes in intracranial pressure. In addition, electromyography provides valuable information on the rate of nerve conduction, and magnetic resonance imaging (MRI) helps to visualize causal damage in the central nervous system.